Nicophon was an Athenian comic poet active during the late 5th and early 4th centuries BCE, a period known as Old Comedy. He is identified as the son of Theronides. His career overlapped with the later work of the famous playwright Aristophanes and the transition toward Middle Comedy. According to the Byzantine encyclopedia known as the Suda, he was a contemporary of another comic poet named Phrynichus. Some sources suggest he may have won victories in dramatic competitions, though this is not certain.

His works survive only in fragments quoted by later authors. The primary source for these fragments is Athenaeus's Deipnosophistae. While the Suda credits him with four plays, only two titles are securely known from the existing fragments: Adonis and Sirens. Both are comedies that draw on mythological themes. Other play titles are sometimes attributed to him, but these attributions are considered doubtful by scholars.

Nicophon is considered a minor figure in the history of Greek comedy. His significance lies in the fact that his fragmentary works help modern scholars understand the broader landscape of Athenian comedy beyond its most famous authors. The fragments, often preserved for their mention of food, drink, or curious details, provide evidence for the thematic range and style of comedy during this transitional period.