Nepoualios is a figure known only from limited metadata, which places him in the 5th or 6th century CE during the late antique period. According to this information, he was a Neoplatonist philosopher with an interest or role in medicine. The combination of philosophy and medical science was not unusual in this era, as some thinkers sought to integrate spiritual and physical understandings of the human body. However, no independent historical records about Nepoualios’s life, education, or specific activities have been found in major scholarly sources.

The metadata suggests he wrote a treatise, but no title or content from this work survives, and its attribution to him cannot be verified. Consequently, his significance within the Neoplatonic tradition or the history of medicine remains unclear. He represents one of many lesser-known intellectuals from late antiquity whose works have been lost to time. Without corroborating evidence, he exists primarily as a name attached to a specific philosophical and medical context from the final centuries of the ancient world.